منابع مشابه
Effects of histones on morphogenesis and differentiation in chick embryos.
The transcription of DNA is known to be inhibited in vitro by the presence of histones. This has been shown to be true for isolated nuclei, isolated chromatin, or for DNA alone (Bonner & Huang, 1962; Bonner, Huang & Gilden, 1963; Allfrey & Mirsky, 1963; Allfrey, Faulkner & Mirsky, 1964; Sonnenberg & Zubay, 1965). The masking of genomic sites in adult differentiated tissues seems the most probab...
متن کاملHistones
JAUNDICE DURING PREGNANCY. By Urs Peter Haemmerli. New York, Springer-Verlag, Inc., 1967. 111 pp. $3.80, paperbound. Jaundice During Pregnancy is an excellent monograph which should be read by all internists, obstetricians, and pediatricians, and which should be available in all medical libraries for ready reference. The author concisely summarizes the known minor alterations of the liver and i...
متن کاملProteins: histones and chromatin.
Patrick Cramer is a professor of Biochemistry at the Ludwig Maximilians University of Munich, Germany, and head of the Gene Center Munich. He is a structural biologist who has contributed to our understanding of the structure and function of RNAP II from yeast and its associated factors. In a recent study, his laboratory described the structure of RNAP II in complex with the initiation factor T...
متن کاملHistones and genome integrity.
Chromosomes undergo extensive structural rearrangements during the cell cycle, from the most open chromatin state required for DNA replication to the highest level of compaction and condensation essential for mitotic segregation of sister chromatids. It is now widely accepted that chromatin is a highly dynamic structure that participates in all DNA-related functions, including transcription, DN...
متن کاملHistones and histone modifications
Imagine trying to stuff about 10,000 miles of spaghetti inside a basketball. Then, if that was not difficult enough, attempt to find a unique one inch segment of pasta from the middle of this mess, or try to duplicate, untangle and separate individual strings to opposite ends. This simple analogy illustrates some of the daunting tasks associated with the transcription, repair and replication of...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1963
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.50.6.1018